Ghobrial Lab - Precursor Hematological Malignancies

Irene M. Ghobrial, M.D.
MICHELE &STEVEN KIRSCH LABORATORY

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International

2017
Immunocheckpoint Inhibitors / Invited speaker, Immunotherapy in Multiple Myeloma:  Accelerating on the Path to the Patient, Havana, Cuba

The Role of the Microenvironment during MGUS Myeloma Transformation / Invited speaker
XVI EMMA meeting, Vienna, Austria

Discussions on Proposals and Next Steps Structures for Collaboration with Egypt and US for Multiple Myeloma / Invited speaker, Egypt/US/EU Multiple Myeloma Educational Meeting, Cairo, Egypt

The Malignant Plasma Cell and Beyond / Invited speaker, IMW Conference, New Delhi, India (Takeda Oncology/IMW)

Understanding the Myeloma Environment / Invited speaker, UK Myeloma Forum (UKMF) Spring Day: Personalized Therapy in Myeloma: Fact or Fiction?, London, England, UK

Understanding the Myeloma Environment / Invited speaker, UKMF Spring Day, Kennedy Institute, Oxford University, Oxford, England, UK

Waldenström Disease / Invited speaker, European Society for Blood and Marrow Transplantation (EBMT) 43rd Annual Meeting, Marseille, France
 
Multiple Myeloma / Plenary Lecture, ASH Day at AMEH, Agrupación Mexicana para el Estudio de la Hematología (Mexican Association for the Study of Hematology) (AMEH), Leon Guanajuanto, Mexico

State of the Art Treatment of Multiple Myeloma / Round Table Discussions, LVIII AMEH National Congress, Leon Guanajuanto, Mexico (Celgene, Mexico)

Lecture Tour on Treatments of High-Risk Myeloma Patients / Single presentation, Israel May Myeloma Speaker Tour, Haifa, Tel Aviv, Jerusalem, Petch Tivka, Beer Sheva, Israel (Bristol Myers Squibb [BMS])

Non-Smoldering Treatments of Smoldering Myeloma / Invited speaker, European School of Hematology, Paris, France

Immunotherapy in Multiple Myeloma / Invited speaker, International Myeloma Working Group, Madrid, Spain

Recent Advances in Myeloma Treatment / Invited speaker, Janssen Haemtology Summit, Dublin, Ireland (Janssen BioScience, Inc.)

2016
From Biology to Clinic / Invited speaker, The 3rd MENA Hematology Meeting, Paris, France (Celgene, France)

The Future in Multiple Myeloma Evolution / Invited speaker, Conference Hematology Oncology Meeting, Cancun, Mexico (Janssen, Mexico)

Are There Familial Aggregation Patterns that Associate with Increased Risk of WM? / Invited speaker, 9th International Workshop on WM, Amsterdam, The Netherlands

Synergistic Mechanism of Action between New Drug Combinations in MM: a Step Forward in Immunomodulation / Invited speaker, LVIII Spanish Society of Hematology and Hematherapy (SEHH), Santiago de Compostela, Spain

2015
Metastatic Myeloma / Invited speaker, 15th International Myeloma Workshop, Rome, Italy

Bone Marrow Microenvironment in Multiple Myeloma / Invited speaker, 10th Myeloma Workshop, Brno, Czech Republic

Effect of Microenvironment on Myeloma / Invited speaker, ESH International Conference, Lisbon, Portugal

Myeloma Involving the Extra-medullary Compartment / Invited speaker, A Weizmann Workshop on Frontiers of Mutiple Myeloma, Rohovot, Israel

The Microenvironment in Myeloma: From Bench to Bedside / Invited speaker, Fourth International Conference: Innovations in Hematology, Jerusalem, Israel

2014
Multiple Myeloma / Invited speaker, Charles University, Prague, Czech Republic

Oprozomib (ONX 0912): An Irreversible Proteasome Inhibitor / Invited speaker

1st Annual Summit on Practical and Emerging Trends in Multiple Myeloma, Whistler, British Columbia, Canada

Molecular Basis for Proteasome Inhibitor / Invited speaker, Multiple Myeloma Symposium, Buenos Aires, Argentina (Johnson and Johnson, Argentina)

Integrating Signal Inhibitors into WM Therapy / Invited speaker, 8th International Workshop on Waldenström’s Macroglobulinemia (IWWM8), London, England, UK

Great Debates in WM – Should Carfilzomib be Given Instead of Bortezomib for WM? / Invited speaker, 8th International Workshop on Waldenström’s Macroglobulinemia (IWWM8), London, England, UK

How I Treat Waldenström's Macroglobulinemia and MGUS / Invited speaker, Cracow III International Conference "Complex Treatment of Plasma cell Dyscrasia in 2014", Cracow, Poland

2013
2013 Highlights of ASH in North America: Plasma Cell Disorders (Myeloma) / Invited speaker,
ASH, Toronto, Ontario, Canada

microRNA in the Biology of Multiple Myeloma / Invited speaker, The XIV International Myeloma Workshop, Kyoto, Japan

Myeloma Metastasis Model / Invited speaker, 4th International Congress on Leukemia Lymphoma Myeloma, Istanbul, Turkey

Waldenström Macroglobulinemia a New Horizon / Invited speaker, Indolent Lymphomas, Meldola, Italy

2012
Treatment of Relapsed and Refractory MM Patient & New Myeloma Therapy and DFCI Experience on Global MM Research Cooperation / Invited speaker, First Janssen-IMF Event, Hong Kong, China (Janssen/IMF)

Molecular Biology of Myeloma and New Therapeutic Approaches / Invited speaker, Monoclonal Gammopathies Workshop, Guanajuato, Mexico

Biology and Therapy in Multiple Myeloma and WM / Invited speaker, National Center for Global Health and Medicine, Tokyo, Japan; Kyoto University, Kyoto, Japan; Kumamoto University, Kyushu, Kumamoto, Japan and Tokushima University, Tokushima, Japan [Same talk at four universities] (NCI, Japan)

Biology and Therapy of Waldenström Macroglobulinemia / Invited speaker, Gunma University, Aramaki-machi, Maebashi City, Japan (Celgene, Japan)

Cell Trafficking in MM / Invited speaker, Cancer Institute, Tokyo, Japan

Studies of Microenvironment in Mice / Invited speaker, V International Workshop on Myeloma, Pharmacogenomics & Novel Therapeutics, Royal College of Physicians, London, England, UK

Advances in the Treatment of Multiple Myeloma and other Plasma Cell Dyscrasias / Invited speaker, Fifth Annual Meeting, Lebanese Society of Hematology and Blood Transfusion, Beirut, Lebanon

Cell Trafficking in Multiple Myeloma / Invited speaker, Chronic Malignancies Working Party, St. Antoine Hospital, Paris, France

2011
Addressing the Unmet Clinical Need in Malignant Lymphoma through Novel Agents Satellite / Invited speaker, 11th International Conference on Malignant Lymphoma (ICML), Lugano, Switzerland

Diagnostics and Biomarker Discovery/Validation / Invited speaker, Science Foundation Ireland, Dublin, Ireland

Role of Novel Agents "in development" in Treating Multiple Myeloma, 3rd Myeloma Workshop Heidelberg, Heidelberg, Germany

2010
Advances in Biology and Therapy in Waldenström Macroglobulinemia / Invited speaker, 6th International Workshop on WM, Venice, Italy

Cell Trafficking in Multiple Myeloma / Invited speaker, 10th International Meeting on Cancer-Induced Bone Disease, Sheffield, UK

Advances in Biology and Therapy in Waldenström Macroglobulinemia / Invited speaker, mTOR Advisory Meeting, Madrid, Spain (Novartis)

2009
Advances in Biology and Therapy in Multiple Myeloma and Waldenström Macroglobulinemia / Invited speaker, Trondheim University, Trondheim, Norway

2008
Novel Therapeutic Agents in Waldenström Macroglobulinemia and Multiple Myeloma / Invited speaker, Hôpital Universitaire Pitié-Salpêtrière, Paris, France

Advances in Biology and Therapy in Multiple Myeloma / Invited speaker, National Myeloma Meeting, Vancouver, Canada

Advances in Biology and Therapy in Waldenström Macroglobulinemia / Invited speaker, International Waldenström Macroglobulinemia Meeting, Stockholm, Sweden

Advances in Biology and Therapy in Waldenström Macroglobulinemia / Invited speaker, Oslo University, Medical Oncology, Oslo, Norway

2007
Novel Therapeutic Agents in Waldenström Macroglobulinemia and Multiple Myeloma / Grand Rounds, Tom Baker Cancer Centre, Department of Oncology, University of Calgary, Calgary, Alberta, Canada

National

2017
Prevention of Progression in Smoldering Myeloma / Invited speaker, Mini-Symposium on Multiple Myeloma, Food and Drug Administration, Silver Spring, MD

Immunotherapy for Smoldering Myeloma / Panelist, Hilton Anatole, Dallas, TX

Are We Integrating Biologic Advances in Multiple Myeloma into Clinical Practice? / Invited speaker, ASCO, Chicago, IL

Targeting the Multiple Myeloma Microenvironment / Invited speaker, FASEB Conference, Saxtons River, VT

2016
3rd Annual Spring to Life Conference on Hematologic Malignancies / Invited speaker, Premyeloma (Descriptions and “How I Treat”), Albany, NY

Defining and Redefining Myeloma / Invited speaker, American Society of Clinical Oncology Convention, Chicago, IL

EPIC Multiple Myeloma in 2016 and Beyond: Expert Round Table Discussions / Discussant, Phoenix, AZ (Medscape)

Prevention of Progression in Multiple Myeloma / Grand Rounds, Memorial Sloan Kettering Cancer Center, New York, NY

MGUS: How to Handle this “Epidemic” / Invited speaker, ASH Consultative Meeting, Chicago, IL

Overview of Multiple Myeloma / Invited speaker, Hematology Oncology Learning Institute (HOLI) Training Course, Charlotte, NC (Medscape)

Prevention of Progression in Multiple Myeloma / Invited speaker, CME Oregon Health & Science University Grand Rounds Invitation, Portland, OR

Blood Biomarkers for Clonal Progression in Multiple Myeloma / Invited speaker, IMF Black Swans Investigators Meeting, San Diego, CA

Translational Science / Invited speaker, Junior Research Symposium, ASH Hematology Convention, San Diego, CA

2015
Multiple Myeloma as a Model of Bone Metastasis / Grand Rounds, Hematology/Oncology Northwestern University, Chicago, IL

Multiple Myeloma as a Model of Bone Metastasis / Invited speaker, Washington University School of Medicine, St Louis, MO

Multiple Myeloma as a Model of Bone Metastasis / Invited speaker, Hematologic Malignancies Demystified, Atlanta, GA, Houston, TX & New York City, NY

Multiple Myeloma as a Model of Bone Metastasis / Invited speaker, The Ohio State University, Columbus, OH

Tumor Microenvironment / Invited speaker, WM Symposium, New York, NY

Multiple Myeloma as a Model of Bone Metastasis / Invited speaker, Grand Rapids, IA

Multiple Myeloma as Model of Bone Metastasis / Invited speaker, Myeloma Case Conference, New York, NY

Timing Transplantation: Now or Later? EPIC Multiple Myeloma in 2015 and Beyond: An Expert RoundTable / Invited speaker, Scottsdale, AZ (Medscape)

Myeloma as a Model of Cell Metastasis / Invited speaker, SOHO Conference, Houston, TX

Multiple Myeloma and Bone Marrow Niche, Best Practices in the Treatment of Patients with Multiple Myeloma / Invited speaker, City of Hope, Los Angeles, CA

Why do Waldenström’s and Myeloma Change from MGUS to Active Disease? The Niche, the Notch and the Nucleus / Invited speaker, Lymphoma and Myeloma, New York, NY

Year in Review 2015: Multiple Myeloma / Invited speaker, Santa Monica, CA (RTP)

Updates in the Treatment of Multiple Myeloma / Invited speaker, Puerto Rico, Ponce, PR

2014
Current Controversies in Multiple Myeloma / Invited speaker, UPMC Cancer Center, Pittsburgh, PA

Hematologic Malignancies Demystified: The Series: A Critical Appraisal of Data / Invited speaker, New York, NY and Washington, DC (Primeoncology)

Multidisciplinary Care of Veterans with Myeloma Series / Invited speaker, Bath VA Medical Center, Bath, NY (CCO)

MGUS and Smoldering Myeloma / Invited speaker, Mayo Clinic, Rochester, MN

Multidisciplinary Care of Veterans with Myeloma Series / Invited speaker,  VA Illiana VA Health Care System, Danville, IL (CCO)

Current Controversies in Multiple Myeloma / Grand Rounds, Oncology Hematology Associates, Gurnee, IL (CCO)

Current Controversies in Multiple Myeloma / Grand Rounds, Novant Health, Derrick L. Davis Cancer Center, Winston-Salem, NC

CME Symposia Series "Meet the Professors", 3 Cases of Multiple Myeloma / Speaker,  Research to Practice, New York City, NY

Multiple Myeloma as a Model of Bone Metastasis / Grand Rounds, Rochester General Hospital, Rochester, NY

Lymphoplasmacytic Lymphoma (Waldenström's) / Invited speaker,  2014 Pan Pacific Lymphoma Conference, Kohala Coast, HI

Multiple Myeloma as a Model of Bone Metastasis / Invited speaker,  Hematologic Malignancies: Translating Discoveries to Novel Therapies, Philadelphia, PA

Current Controversies of Multiple Myeloma / Invited speaker,  CMM Multiple Myeloma Program, Beaumont Cancer Center, Royal Oak, MI (CCO)

Multiple Myeloma as a Model of Bone Metastasis / Invited speaker, “Bridging the Gap from Bench to Bedside:  The Road to Cures”, The Leukemia & Lymphoma Society Research Symposium, Washington, DC

Multiple Myeloma as a Model of Bone Metastasis / Grand Rounds, Department of Medcine, Rochester General Hospital, Rochester, NY

Multiple Myeloma as a Model of Bone Metastasis / Invited speaker, AACR Hematologic Malignancies: Translating Discoveries to Novel Therapies, Philadelphia, PA

Multiple Myeloma: A Year in Review / Invited speaker, CME Best Practices in the Treatment of Patients with Multiple Myeloma Orlando, FL CME, Research to Practice (RTP)

Multiple Myeloma: A Year in Review / Invited speaker, RCME Best Practices in the Treatment of Patients with Multiple Myeloma, Interfaith Medical Center, Brooklyn, NY (RTP)
 
The Myeloma Niche and the Immunobiology of Myeloma / Invited speaker, ASH, San Francisco, CA

Laboratory & Translational Hematology Careers / Invited speaker,  ASH, San Francisco, CA

2013
2013 Highlights of ASH in North America: Plasma Cell Disorders (Myeloma) / Invited speaker,
ASH, Miami, FL

Cell Trafficking in Multiple Myeloma / Invited speaker, AFCRI/Hem-Onc Seminar the University of Pennsylvania, Philadelphia, PA

Advances in the Treatment of Patients with Multiple Myeloma / Invited speaker, Minnesota Society of Clinical Oncology, Minneapolis, MN

Progress in WM Building Blocks – Cell Lines, Tissue Bank, 2013 Mouse Models / Invited speaker, IWMF Educational Forum, San Diego, CA

Myeloma as a Model of Cell Metastasis / Grand Rounds, Roswell Park Cancer Institute, Buffalo, NY

Myeloma as a Model of Cell Metastasis / Grand Rounds, University of Texas Health Science Center at San Antonio, San Antonio, TX

HDAC Inhibition in Multiple Myeloma (MM) / Invited speaker, Multiple Myeloma Expert Roundtable, Scottsdale, AZ (Medscape)

Waldenström’s Macroglobulinemia: Emerging New Drugs and Clinical Trials / Invited speaker, 18th Annual North American Educational Forum on Lymphoma, Brooklyn, NY

Waldenström's Macroglobulinemia Therapy in the Era of Novel Therapies / Invited speaker, Lymphoma and Myeloma 2013, an International Congress on Hematologic Malignancies, New York, NY

Emerging Strategies in the Management of Multiple Myeloma / Grand Rounds, John T. Mather Memorial Hospital, Port Jefferson, NY

2012
MM Relapsed/Refractory / Invited speaker, Hematologic Malignancies Demystified, Atlanta, GA (Primeoncology)

MM Relapsed/Refractory / Invited speaker, Hematologic Malignancies Demystified, Houston, TX (Primeoncology)

Optimizing Care for Patients with Relapsed/Refractory Multiple Myeloma / Invited speaker, Howard University Hospital, Washington DC (Medscape)

MM Relapsed/Refractory / Invited speaker, Jackson Cancer Center, Jackson, MS (Primeoncology)

Track Designations: Primary: Lymphoma and Plasma Cell Disorders / Invited speaker, ASCO, Chicago, IL

Optimizing Care for Patients with MM Relapsed/Refractory / Invited speaker, Southern Ohio Medical Center, Portsmith, OH (CME, Educational Concepts Group (ECG)

Optimizing Care for Patients with MM Relapsed/Refractory / Invited speaker, Albuquerque Cancer Center, Albuquerque, NM (ECG)

Multiple Myeloma: Case-Based Workshops with the Experts / Invited speaker, Halifax Health Center for Oncology, Quintiles, Daytona Beach, FL (CCO)

Optimizing Care for Patients with Relapsed/Refractory Multiple Myeloma / Invited speaker, Mercy Medical Center, Rockville Centre, NY (ECG)

2011
Updates on the Biology and Treatment of Waldenström Macroglobulinemia / Invited speaker, The Physician and Patient Summit for WM, Buena Vista Hotel, Orlando, FL

Updates on Treatment of Multiple Myeloma / Invited speaker, Veterans Affairs Hospital, Montgomery, AL (CCO)

Advances in the Management of Multiple Myeloma / Invited speaker, Emory University, Atlanta, GA (CCO)

Cell Trafficking in Multiple Myeloma / Invited speaker, MD Anderson Cancer Center, Houston, TX

Advances in the Management of Multiple Myeloma: A CaseMat Approach / Invited speaker, University of Nebraska, Lincoln, NE (Medscape)

Mechanisms of Plasma Cell Dyscrasias / Invited speaker, FASEB Summer Research Conference: Hematopoietic Malignancies, Saxtons River, VT

Advances in the Management of Multiple Myeloma: A CaseMat Approach / Invited speaker, Educational Concepts Lecture Series, Temple, TX (Medscape)

Lymphoma – Pre-Clinical – Chemotherapy and Biologic Agents: Novel Targeted Therapy of B-cell Malignancies / Invited speaker, ASH, San Diego, CA

2010
Regulation of Cell Trafficking in Multiple Myeloma / Invited speaker, Leukemia and Lymphoma Society symposium on Tumor Microenvironment, American Society of Hematology, Orlando, FL

Updates in Multiple Myeloma / Invited speaker, Cleveland Clinic ASH Review, Cleveland, OH

Advances in the Management of Multiple Myeloma / Invited speaker, Moffitt Cancer Center, Tampa, FL (CCO)

Advances in the Management of Multiple Myeloma / Invited speaker, Kimmel Cancer Center, Camden, NJ (CCO)

Multiple Myeloma Phase II Investigator Meeting PANORMA (PANobinostat ORAl in Multiple MyelomA) / Invited speaker, Simon Cancer Center, East Hanover, NJ

Advances in the Management of Multiple Myeloma: A CaseMat Approach / Invited speaker, MD Anderson, Houston, TX (Medscape)

Advances in the Management of Multiple Myeloma / Invited speaker, Sylvester Cancer Center, Miami, FL (CCO)

Updates on the Biology and Treatment of Waldenström Macroglobulinemia / Invited speaker, The Lymphoma and Myeloma 2010 Conference, New York, NY

Advances in the Management of Multiple Myeloma / Invited speaker, San Juan Cancer Center, San Juan, PR (CCO)

2009
Updates on Novel Agents in Waldenström Macroglobulinemia / Invited speaker, International Waldenström Macroglobulinemia Foundation, Educational Forum, Memphis, TN

Updates in the Treatment of Multiple Myeloma / Grand Rounds, James A. Haley VA Hospitals, Tampa, FL (CME - Clinical Care Options) (CCO)

Update on Upfront Therapeutic Options in MM / Invited speaker, Brunswig Hospital, Brunswig, NY (Medscape)

Updates on Biology and therapy in Waldenström Macroglobulinemia / Invited speaker, PanPacific Lymphoma Conference, Honolulu, HI

Cell Trafficking in Multiple Myeloma /Grand Rounds, Moffitt Cancer Center, Tampa, FL

Updates in the Treatment of Multiple Myeloma / Grand Rounds, Amarillo VA Healthare System, Amarillo, TX (CCO)

Updates in the Treatment of Multiple Myeloma /Grand Rounds, VA Healthcare System, Naples, FL (CCO)

Updates in the Treatment of Multiple Myeloma /Grand Rounds, VA Healthcare System, Providence, RI (CCO)

Cell Trafficking in Multiple Myeloma / Invited speaker, Lymphoma and Myeloma 2009, International Meeting on Hematological Malignancies, New York, NY

2008
NCCN Guidelines for Multiple Myeloma in Relapsed or Refractory MM / Invited speaker, NCCN meeting, Miami, FL (Medscape)

Post-ASH Updates on Multiple Myeloma and Waldenström Macroglobulinemia, 2009 Hematology Highlights / Invited speaker, The University of Nebraska Medical Center, Omaha, NE

Updates in the Treatment of Multiple Myeloma / Grand Rounds, James A. Haley VA Hospitals, Tampa, FL

Cell Trafficking in Multiple Myeloma / Invited speaker, Sloan Kettering Cancer Center, New York, NY

2007
Novel Therapeutic Agents in Multiple Myeloma and Waldenström’s Macroglobulinemia / Invited speaker, Hematology and Oncology Grand Rounds, Winship Cancer Institute, Atlanta, GA

Novel Therapeutic Agents in Multiple Myeloma and Waldenström’s Macroglobulinemia / Invited speaker, Post-ASH CME/CE, Fairbanks Hotel, Rumson, NJ

Novel Therapeutic Agents in Multiple Myeloma and Waldenström’s Macroglobulinemia / Invited speaker, University of Utah, Salt Lake City, UT

Novel Therapeutic Agents in Multiple Myeloma and Waldenström’s Macroglobulinemia / Invited speaker, UNM Cancer Center, Albuquerque, NM

Novel Therapeutic Agents in Multiple Myeloma and Waldenström’s Macroglobulinemia / Invited speaker, Clinical Breakthroughs and Challenges in Hematologic Malignancies, Buena Vista Hotel, Lake Buena Vista, FL (Moffitt Cancer Center, Tampa, FL)

Novel Therapeutic Agents in Multiple Myeloma and Waldenström’s Macroglobulinemia / Invited speaker, University of Nebraska, Omaha, NE

Novel Therapeutic Agents in Multiple Myeloma / Invited speaker, ASH Update Meeting and Case Presentations, Northwestern University, Chicago, IL

Novel Therapeutic Agents in Waldenström’s Macroglobulinemia / Invited speaker, Leukemia and Lymphoma WM and Myeloma Support Group, Denver, CO

Multiple Myeloma: Translating the Evidence into Clinical Practice / Invited speaker, New Hanover Regional Center, Wilmington, NC (Medscape)

Multiple Myeloma: Translating the Evidence into Clinical Practice / Invited speaker, Bon Secours DePaul Medical Center, Norfolk, VA (Medscape)

Multiple Myeloma: Translating the Evidence into Clinical Practice / Invited speaker, Mount Sinai Medical Center, Tarrytown, NY (Medscape)

Newer Approaches in the Treatment of Multiple Myeloma: Do Emerging Therapies Offer an Advantage / Invited speaker, Hawthorn Cancer Center, Portsmouth, RI (Medscape)

2006
Novel Therapeutic Agents in Multiple Myeloma and Waldenström’s Macroglobulinemia / Invited speaker, CME activity, George Cancer Foundation, Atlanta, GA

Novel Therapeutic Agents in Multiple Myeloma and Waldenström’s Macroglobulinemia / Invited speaker, CAMC Health Education and Research Institute, Charleston, WV

2005
Novel Therapeutic Agents in Multiple Myeloma / Invited speaker, Department of Hematology/Oncology, Cleveland Clinic, Cleveland, OH

Update on Novel Therapies for Multiple Myeloma / Invited speaker, Department of Hematology/Oncology, University of Pittsburgh, Pittsburgh, PA

2000
Comparison of Intracellular Signaling Pathways on Bcl-2 Regulation of Endothelial Cells Stimulated by Angiogenic and Angiostatic Chemokines of the CXC Family / Invited speaker, Mayo Clinic Balfour Surgical Research Symposium, Rochester, MN
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