Ghobrial Lab - Cell Metastasis or Cell Dissemination in Hematological Malignancies

Irene M. Ghobrial, M.D.
MICHELE &STEVEN KIRSCH LABORATORY

  • Home
  • Our Lab
    • About Our Lab
    • Current Projects
    • Awards
  • Our Team
    • Leadership
    • Lab Team
    • Clinical Team
    • Alumni
    • Photo Gallery
  • Lectures and Conferences
  • Publications
    • 2019
    • 2018
    • 2017
    • 2016
    • 2015
    • 2014
    • 2011, 2012 & 2013
    • 2010
    • 2009
  • News
  • Videos
  • Support
  • Contact Us

Ghobrial Lab Research

Our current research focuses around multiple aspects of cell metastasis or cell dissemination in hematological malignancies and their interactions with the bone marrow niches including: 
  • Mechanisms of early cell dissemination and clonal heterogeneity.
  • The role of circulating tumor cells and circulating exosomes in cell dissemination.
  • Preparation of the metastatic niche for tumor colonization.
  • Factors that regulate progression of micro-metastasis in patients with MGUS to overt MM.
  • miRNA regulators of tumor dissemination and stromal/myeloma interaction for cell dissemination.
  • Mechanisms of cell dissemination in extramedullary MM.
  • The role of the bone marrow niche in regulating drug resistance in MM.
          HOME  | OUR LAB  |  OUR TEAM |  LECTURES AND CONFERENCES  | PUBLICATIONS  | NEWS | SUPPORT | CONTACT US

© 2018 Ghobrial Lab at Dana-Farber Cancer Institute